Understanding Voglibose: Uses, Benefits, and Side Effects

Voglibose is an oral anti-diabetic medication that belongs to alpha-glucosidase inhibitors. It helps lower postprandial blood glucose levels, making it easy to control diabetes. All these medicines, i.e., Volibo, Volix, and  Voglitor MD, have the same active ingredient, Voglibose. They all are used to treat type-2 diabetes mellitus. Type-2 diabetes is a non-insulin-dependent diabetes; patients can take these drugs and also work on their diet and physical exercise to have regular blood sugar and diagnose the condition. Voglibose was discovered and formulated in 1981 by Takeda Pharmaceutical Company, a Japan-based pharmaceutical company.

Voglibose uses?

Voglibose is a valiolamine derivative and an alpha-glucosidase inhibitor with antihyperglycemic activity. Volibo M 0.3/500 mg delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting carbohydrate digestive enzymes like sucrose, maltose, maltase, etc. Diabetes is a medical condition in which blood glucose levels are above normal. Doctors prescribe Voglibose dosage to diabetes patients depending on their medical condition. Voglibose increases the release of GLP-1, an insulinotropic hormone known to enhance insulin secretion and sensitivity.

How does Voglibose work?

Volibo M 0.2/500mg or Volibo M 0.3/500 mg works by inhibiting the intestinal enzymes, alpha-glucosidase, in the intestines, which break complex sugars into simple sugars like glucose. Therefore, this medication slows down glucose absorption from the digestive tract into the bloodstream and prevents blood glucose levels from rising immediately after meals. In other words, voglibose tablets can bind and inhibit alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines, that hydrolyses oligosaccharides and disaccharides into glucose and other monosaccharides. Therefore, this medication prevents the breakdown of larger carbohydrates into glucose to control blood glucose. Voglibose may also facilitate mobilisotary α endogenous glycogen like peptide 1 (GLP-1), which has an inhibitory action on glycogen, thus preventing glucose levels in your body.

Benefits of Voglibose:

Voglibose and metformin are anti-diabetic medicines and are largely prescribed to be taken before each meal. Voglibose 0.2 is used to treat postprandial hyperglycemia, which controls glucose in the blood. Usually, Voglibose and other drugs like sulfonyl or metformin are used to prevent glucose levels. You can take this medicine and continue exercising and taking other anti-diabetic measures. You can find better results in controlling blood sugar if generic metformin hcl or Volix M 0.3/500mg is taken along with insulin. Volibo M 0.3/500 mg tablets are also recommended to treat steroid-induced diabetes with a controlled diet. Do not take any diabetes medicine without consulting a doctor.

voglibose and metformin

Dosage and administration of Voglibose:

Voglibose tablet can be taken alone or in combination with other anti-diabetic medications like metformin, sulfonylureas, or insulin for controlling postprandial blood glucose levels in individuals with type 2 diabetes mellitus. The dosage and administration of Voglibose tablets depend on the condition, tolerance, and effectiveness of the individual diabetes patient. Follow the prescribed dosage to get the most from this medicine. The maximum Voglibose 0.2 mg or 0.6 mg tablet should not exceed three times a day. This dose effectively decreases the reaction of VAT (visceral adipose tissue) to SATC (Subcutaneous Adipose Tissue).

It is recommended to take this medicine before meals as it is proven to be very effective in controlling blood sugar spikes after taking a meal. Generic Voglibose and metformin tablets can be co-administered in conjunction with diet treatment or diet along with oral hypoglycaemic drugs. In non-diabetic hyperinsulinemia and steroid-included diabetes, Voglibose 0.2mg tablet can be given before meals. For insulin-dependent diabetes mellitus (IDDM) patients, a dose of Volix M 0.2/500mg to Volix M 0.3/500mg is recommended before meals, and insulin administration can be continued throughout the process.

Side effects of Voglibose:

Some common side effects of Voglibose tablets include gastrointestinal disturbances – abdominal pain, bloating, flatulence, and diarrhea due to the fermentation of undigested carbohydrates in the gut. Some rare side effects of Voglibose and metformin are hypoglycemia (low blood sugar) and skin rashes when used in combination with other anti-diabetic drugs.

Precautions with Voglibose:

Tab Voglibose should be taken under prescription, and people with certain health conditions like bowel disease, intestinal obstruction, or severe renal impairment should inform their doctor before taking this medicine. Regular monitoring of your blood glucose levels is essential for appropriately adjusting the dosage of voglibose and metformin tablets.

Volibo M 0.2/500mg and 0.3/500 mg are effective and safe for managing postprandial blood sugar spikes for type 2 diabetes patients. It is advised that the correct dosage of Voglibose be taken under the guidance of a healthcare professional to achieve the desired results.